Hyderabad*
Piramal Pharma Solutions offers development and manufacturing services for large molecules through an investment in Yapan Bio Private Limited. Based in Genome Valley in Hyderabad, India, Yapan Bio has a proven track record of success in developing and manufacturing a variety of large molecule therapeutics. Yapan provides process development, scale-up, and GMP compliant manufacturing of vaccines and biologics/bio-therapeutics, including high containment product classes (up to BSL-2+), recombinant vaccines, RNA/DNA vaccines, gene therapies, monoclonal antibodies, therapeutic proteins, and other complex biologics.
221 and 222, Building 450, MN Park, Synergy Square 1, Genome Valley, Shamirpet, Hyderabad – 500078 Telangana, India
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Vaccines
- Recombinant Vaccines (Protein Antigens, Virus Like Particles, Nano-Particles, etc.)
- Viral Vector Based Vaccines
- RNA/DNA Vaccines
Biologics/Bio-Therapeutics
- Gene Therapy
- Oncolytic Viruses
- Vectors (Viral & Non-Viral), etc.
- Monoclonal Antibodies
- Therapeutic Proteins and Other Complex Biologics
Process Development
- Optimization and Scale-Up for High Product Titer, Stability and Consistent Manufacturing Output
- Upstream and Downstream Development
- Analytical Method Development and Qualification
GMP Manufacturing
- Cell and Virus Seed Banking
- Rocker, Stirred Tank and Adherent Cell Bioreactors
- Utilization of Single-Use Technologies
- Up to 200L Bioreactor Scale (500L in Q1 2023)
- Facility for High Containment/Infectious Agents (BSL-2+)
- Fill/Finish On-Site: Aseptic Formulation, Fill & Finish (Lyophilization & Liquid in Vials)
Process Characterization:
- Establishment and Qualification of Small-Scale Model for Different Unit Operations for the Process
- Classification of Process Parameters and Product Quality Attributes-Critical, Major, Minor
- Design of Experiments (DoE) to Establish the Appropriate Ranges for the Process Parameters and Product Quality Attributes
- Execution of Experiments and Generation of Data/Reports to Support Regulatory Filings
Location Address:
GMP Facility: 221 and 222, Building 450, Synergy Square 1, Genome Valley, Shamirpet, Hyderabad – 500078 Telangana, India
Process Development Facility: 270 Touchstone, Genome Valley, Shamirpet, Hyderabad – 500078, Telangana, INDIA
Contact: +91 9154313861-4
