Hyderabad**

Piramal Pharma Solutions offers development and manufacturing services for large molecules through an investment in Yapan Bio Private Limited. Based in Genome Valley in Hyderabad, India, Yapan Bio has a proven track record of success in developing and manufacturing a variety of large molecule therapeutics. Yapan provides process development, scale-up, and GMP compliant manufacturing of vaccines and biologics/bio-therapeutics, including high containment product classes (up to BSL-2+), recombinant vaccines, RNA/DNA vaccines, gene therapies, monoclonal antibodies, therapeutic proteins, and other complex biologics.

Location Address:

221 and 222, Building 450, MN Park, Synergy Square 1, Genome Valley, Shamirpet, Hyderabad – 500078 Telangana, India

Contact: +91-40-23480049

Vaccines

  • Recombinant Vaccines (Protein Antigens, Virus Like Particles, Nano-Particles, etc.)
  • Viral Vector Based Vaccines
  • RNA/DNA Vaccines

Biologics/Bio-Therapeutics

  • Gene Therapy
    • Oncolytic Viruses
    • Vectors (Viral & Non-Viral), etc.
  • Monoclonal Antibodies
  • Therapeutic Proteins and Other Complex Biologics

Process Development

  • Optimization and Scale-Up for High Product Titer, Stability and Consistent Manufacturing Output
  • Upstream and Downstream Development
  • Analytical Method Development and Qualification

GMP Manufacturing

  • Cell and Virus Seed Banking
  • Rocker, Stirred Tank and Adherent Cell Bioreactors
  • Utilization of Single-Use Technologies
  • Up to 200L Bioreactor Scale (500L in Q1 2023)
  • Facility for High Containment/Infectious Agents (BSL-2+)
  • Fill/Finish On-Site: Aseptic Formulation, Fill & Finish (Lyophilization & Liquid in Vials)

Process Characterization:

  • Establishment and Qualification of Small-Scale Model for Different Unit Operations for the Process
  • Classification of Process Parameters and Product Quality Attributes-Critical, Major, Minor
  • Design of Experiments (DoE) to Establish the Appropriate Ranges for the Process Parameters and Product Quality Attributes
  • Execution of Experiments and Generation of Data/Reports to Support Regulatory Filings

Location Address:

GMP Facility: 221 and 222, Building 450, Synergy Square 1, Genome Valley, Shamirpet, Hyderabad – 500078 Telangana, India
Process Development Facility: 270 Touchstone, Genome Valley, Shamirpet, Hyderabad – 500078, Telangana, INDIA
Contact: +91 9154313861-4

Virtual Tour
Take a virtual tour of our Yapan Bio plant.
Virtual Tour
Take a virtual tour of our Yapan Bio plant II.