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Antibody-drug conjugates (ADCs) have rapidly evolved into a major oncology therapeutic modality, driven largely by advancements in bioconjugate chemistry and payload-linker design. While early ADC development faced setbacks, recent innovations have unlocked greater selectivity, safety, and clinical success. Today, payload-linker technologies play a defining role in differentiating ADC candidates within increasingly competitive pipelines.
Jan 22, 2026
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Oral liquid formulations are a vital drug delivery format, renowned for their ease of swallowing, rapid onset of action, and dosing flexibility. They are especially important for pediatric and geriatric populations, but present unique formulation challenges that require specialized expertise and integrated drug development capabilities.
Jan 21, 2026
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Clinical manufacturing is the production of drug substances and drug products under strictly controlled conditions for use in clinical trials. It ensures that experimental therapies meet rigorous quality, safety, and regulatory standards before they are tested in humans. Many pharmaceutical developers partner with a pharmaceutical CDMO to access specialized expertise, state-of-the-art facilities, and experience in the efficient and consistent production of clinical materials.
Jan 19, 2026
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Small molecule drugs are low-molecular-weight compounds that can readily enter cells to modulate biological processes. They form the foundation of many treatments across therapeutic areas, including cardiovascular and metabolic diseases, oncology, and infectious diseases. Their relatively simple structure, compared to that of biologics, allows for oral administration, easier formulation, and cost-effective production. Understanding small molecule development is critical for companies aiming to deliver effective therapies efficiently.
Jan 16, 2026
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Lyophilization, also known as freeze-drying, is a critical technology for improving the stability and shelf life of drug products, including biologics and other complex modalities. Many drug substances that demonstrate strong biological activity struggle to remain stable in solution long enough to meet the 24-month shelf life typically required for commercial viability. Lyophilization addresses this challenge by converting liquid formulations into dry, solid products that can be stored and transported under refrigerated conditions rather than frozen, reducing logistical complexity.
Jan 14, 2026
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