Yapan Bio

Piramal Pharma Solutions offers development and manufacturing services for large molecules through an investment in Yapan Bio Private Limited. Based in Genome Valley in Hyderabad, India, Yapan Bio has a proven track record of success in developing and manufacturing a variety of large molecule therapeutics. Yapan provides process development, scale-up, and GMP compliant manufacturing of vaccines and biologics/bio-therapeutics, including high containment product classes (up to BSL-2+), recombinant vaccines, RNA/DNA vaccines, gene therapies, monoclonal antibodies, therapeutic proteins, and other complex biologics.

Location Address:

221 and 222, Building 450, MN Park, Synergy Square 1, Genome Valley, Shamirpet, Hyderabad – 500078 Telangana, India

Contact: +91-40-23480049


  • Recombinant Vaccines (Protein Antigens, Virus Like Particles, Nano-Particles, etc.)
  • Viral Vector Based Vaccines
  • RNA/DNA Vaccines


  • Gene Therapy
    • Oncolytic Viruses
    • Vectors (Viral & Non-Viral), etc.
  • Monoclonal Antibodies
  • Therapeutic Proteins and Other Complex Biologics

Process Development

  • Optimization and Scale-Up for High Product Titer, Stability and Consistent Manufacturing Output
  • Upstream and Downstream Development
  • Analytical Method Development and Qualification

GMP Manufacturing

  • Cell and Virus Seed Banking
  • Rocker, Stirred Tank and Adherent Cell Bioreactors
  • Utilization of Single-Use Technologies
  • Up to 200L Bioreactor Scale (500L in Q1 2023)
  • Facility for High Containment/Infectious Agents (BSL-2+)
  • Fill/Finish On-Site: Aseptic Formulation, Fill & Finish (Lyophilization & Liquid in Vials)

Salient Features:

  • Establishment and Qualification of Small-Scale Model for Different Unit Operations for the Process
  • Classification of Process Parameters and Product Quality Attributes-Critical, Major, Minor
  • Design of Experiments (DoE) to Establish the Appropriate Ranges for the Process Parameters and Product Quality Attributes
  • Execution of Experiments and Generation of Data/Reports to Support Regulatory Filings
Virtual Tour
Take a virtual tour of our Yapan Bio plant.