Knowledge Hub

What is GMP Manufacturing? Key Principles and Benefits Explained

Good Manufacturing Practice (GMP) is the foundation of quality in the pharmaceutical industry. It ensures that biopharmaceutical products are consistently produced and controlled according to the highest quality standards, minimizing risks such as contamination, deviations, or mix-ups during production. 

Nov 24, 2025

How Process Development Drives Successful Drug Manufacturing

In the complex journey from molecule to medicine, process development serves as the critical bridge between scientific discovery and full-scale manufacturing. It transforms laboratory methods into scalable, reproducible, and compliant processes, ensuring that every batch of drug product meets the highest standards of quality, safety, and efficacy.

Nov 20, 2025

How Project Management Can Make or Break a CDMO

In the pharmaceutical CDMO industry, precision and timing are everything. From discovery to commercialization, each stage of a program depends on seamless coordination among scientists, engineers, and regulatory experts. Behind that coordination is a critical function that often determines success or failure - project management.

Nov 17, 2025

Selecting a CDMO: Best Practices for Pharma Innovator Companies

For pharma innovators, bringing a new therapy to market requires more than scientific insight; it demands a strategic partnership with a CDMO that can support the full scope of development and manufacturing.

Nov 14, 2025

Formulation Challenges for High-Potency and Hormonal Drugs

The development of high-potency active pharmaceutical ingredients (HPAPIs) and hormonal drugs represents one of the most demanding areas in modern pharmaceutical manufacturing. 

Nov 05, 2025

Accelerating Drug Discovery with Custom Synthetic Chemistry Solutions

In today's competitive pharmaceutical landscape, speed and precision are crucial for transforming promising concepts into viable drug candidates. Yet, the path from hit identification to optimized lead is often hindered by complex structure–activity relationship (SAR) studies, demanding synthesis requirements, and iterative cycles of testing and refinement.

Oct 31, 2025

Formulating for Success: Innovations in Oral Solid Dosage Forms

Oral Solid Dosage (OSD) forms – such as tablets and capsules – remain the backbone of modern pharmaceuticals. They are stable, scalable, and preferred by patients for their convenience and ease of administration.

Oct 28, 2025

The Future of Pharma CDMOs: From Chemistry Experts to Strategic Innovators

For decades, Contract Development and Manufacturing Organizations (CDMOs) have been valued primarily for their expertise in chemistry and processes, alongside specialized skills in scale-up, synthesis, and compliance. But as the pharmaceutical landscape becomes increasingly complex and patient-centered, the expectations placed on CDMOs are rapidly evolving.

Oct 24, 2025

Accelerating API Development with Smart Route Scouting Strategies

In the race to bring new therapies to market, active pharmaceutical ingredient (API) development is often where timelines are made or lost. Efficient synthesis, scalability, and regulatory readiness all hinge on one critical step: identifying the most effective route of synthesis. 

Oct 16, 2025

Why ADC Fill/Finish Services are Vital to Biopharma Success

Antibody-Drug Conjugates (ADCs) have rapidly emerged as one of the most promising therapeutic classes in pharmaceuticals, particularly in oncology. By combining the targeting power of monoclonal antibodies (mAbs) with the potency of cytotoxic payloads, ADCs offer precision treatment options with reduced off-target effects.

Oct 13, 2025

Peptide Synthesis & Manufacturing: A Step-by-Step Journey from Discovery to Production

Peptides are short chains of amino acids that play a natural role in many biological processes. In recent years, they have become an increasingly important class of therapeutics due to their specificity, versatility, and low toxicity. As a result, peptide APIs are now at the center of modern drug discovery and development.

Oct 01, 2025

How Integrated Drug Discovery Platforms Reduce Time to Market

Drug discovery and development involve multiple interconnected steps, including identifying promising candidates, developing formulations, conducting clinical research, seeking regulatory approvals, and scaling-up manufacturing.

Sep 26, 2025

Challenges in Antibody-Drug Conjugate Manufacturing and How CDMOs Solve Them

Antibody-Drug Conjugates (ADCs) are rapidly gaining prominence in oncology and targeted therapeutics because they deliver highly potent drugs directly to diseased cells while minimizing collateral damage to healthy tissues.

Sep 22, 2025

Drug Development in 2025: Key Trends Shaping the Future of Pharma

Innovation has always been a vital component of the pharmaceutical industry. Today, drug discovery and development are entering a new phase, powered by advanced technologies, precision approaches, and global collaboration.

Sep 16, 2025

The Role of a Biologics CDMO: Navigating the Complex World of Large Molecule Drug Development

A Contract Development and Manufacturing Organization (CDMO) plays a pivotal role in the biologics manufacturing process. These organizations provide outsourced services to pharmaceutical and biotech companies, helping them develop and produce biologic drugs that treat various medical conditions.

Aug 19, 2025

Why Formulation Development Matters: Turning Concepts into Life-Saving Therapies

Formulation development is the process that transforms scientific concepts into effective, market-ready drug products. It bridges the gap between a pharmaceutical idea and a tangible therapy that patients can use to treat or manage diseases.

Aug 12, 2025

Why Analytical Development in Pharma Is Essential for Safe, Effective Drug Manufacturing

In the drug manufacturing process, ensuring the safety, quality, and effectiveness of a pharmaceutical product is crucial. From the development of active pharmaceutical ingredients (APIs) to the manufacturing of a final drug product, the entire journey requires careful testing and validation. 

Aug 08, 2025

The Pharmaceutical Supply Chain: A Critical Component of Drug Delivery

The pharmaceutical supply chain is a complex network that encompasses the production and distribution of medications from manufacturers to end-users, including hospitals, pharmacies, and patients. This supply chain ensures that life-saving drugs are available at the right time and place, in the proper dosage and quality.

Aug 05, 2025

What Is a CDMO vs. a CRO? Understanding Their Roles in Drug Development

In drug development, two key partners are CDMOs and CROs. While their roles may overlap, CDMOs focus on drug formulation and manufacturing, while CROs specialize in research and clinical trial management. Understanding their differences is essential for navigating the drug development process.

Aug 01, 2025

The Role of High Potency APIs in Oncology Drug Development: A Deep Dive

High Potency Active Pharmaceutical Ingredients (HPAPIs) are vital in oncology, allowing the production of targeted cancer therapies. These compounds deliver effective treatment at low doses, making them essential for minimizing adverse effects while maximizing therapeutic impact.

Jul 30, 2025

Quality Control and Compliance in Sterile Injectables Manufacturing

Sterile injectables manufacturing is critical in delivering safe and effective parenteral drugs, especially as the demand for these products rises. Ensuring quality control and compliance is paramount, as these factors are essential in preventing contamination and ensuring drug stability.

Jul 25, 2025

Patient Centricity: Driving Compassionate Innovation Across Our Services

At Piramal Pharma Solutions, our mission is to help our clients with their quest to reduce the burden of disease for patients worldwide. Every day, we commit ourselves to doing well and doing good, ensuring that patients are the primary beneficiaries of our efforts.

Jul 18, 2025

The Role of Antibody-Drug Conjugates in Drug Development

Antibody-drug conjugates (ADCs) represent a significant advancement in drug development, combining the targeting ability of antibodies with the cytotoxic potential of chemotherapy. These innovative therapies deliver potent drugs directly to cancer cells, minimizing damage to healthy tissues.

Jul 17, 2025

Project Risk Management And Strategies For Mitigation

In the CDMO industry, 100% of projects encounter unforeseen challenges (risks), which can lead to increased costs, delays in meeting milestones, or changes in the scope of activity. Hence, risk management needs to be seen as a beacon that steers the course correction of projects. As a guiding light, risk management needs to be addressed and embraced throughout the life cycle of a project.

Why Are Proposals So Important?

Proposals are a critical part of a business because they are the starting point in the business’s evolution from concept to reality. Without knowing how to prepare and write proposals, the business will never be able to get off the ground successfully. While this is true for many industries, it is particularly relevant for a contract development and manufacturing organization (CDMO) serving the biopharma market. A successful CDMO begins with the ability to deliver a winning proposal.

Six Considerations For Success When Sourcing Your Cmc Programming

80% of NMEs in clinical developments are outsourced by small pharma companies every year out of the 13,500+ preclinical/clinical programs in 2020/21 in the pharmaceutical industry. This leads to an ever growing need to find, nurture and partner with the right contract development and manufacturing organization (CDMO). With a 9 to 12-month window to file an IND and similar aggressive timelines for other phases of clinical programs, that’s a lot to get done in a very short time!

CUSTOMER CENTRICITY: ASCERTAINING CUSTOMER NEEDS DURING CHANGING TIMES

The focus on customers and their needs is central to the success of any organization. Delivering a delightful customer experience is not only expected, it’s essential for any business that hopes to progress.

Operational Excellence: Delivering Value To Customers, Patients & Shareholders

Operational Excellence (OE) is one of the key elements of organizational leadership and organizational intelligence. It focuses on delivering maximum value to customers and stakeholders. For a Contract Development and Manufacturing Organization (CDMO) operating in the pharmaceutical industry, the focal point of Operational Excellence essentially is serving patients and customers efficiently in aspects of Safety, Quality, Delivery and Cost.

SUPPLY CHAIN MANAGEMENT : SUSTAINABILITY INITIATIVES FOR CDMOs

Sustainability is a crucial element of today’s Supply Chain Management (SCM). When designing supply chain strategies, it is essential to keep in mind responsible business practices and the commitment to society for a cleaner, safer environment.

BUILDING A CULTURE OF SAFETY AND SAFETY PSYCHOLOGY WITHIN AN ORGANIZATION

Most of you are probably aware of the well-documented case of The Piper Alpha oil platform disaster of 1988, where absence of adequate maintenance and risk assessment led to the loss of 167 lives. Another major industrial accident, the catastrophi...

PARADIGM SHIFT: REMOTE AUDITS DURING THE COVID PANDEMIC

Traditionally, most pharmaceutical companies have preferred to conduct on-site audits of their vendor partners. Seeing the partner’s facility in person and meeting the people who will be handling your product has be...

How to develop a successful regulatory partnership with a CDMO

A CDMO plays a critical role in developing and finalizing the CMC section of your regulatory filing. An experienced and technically sound regulatory team at the CDMO is a valuable partner in ensuring a swift and seamless product approval by variou...

What does a pharmaceutical integrated services program entail? Key attributes to look for in an integrated services provider.

As drug development gets ever more competitive, complex and costly, innovator and generic pharma companies are increasingly choosing contract development and manufacturing organizations (CDMOs) to streamlin...

Investigative Report Writing

According to a report by the FDA (FY2010), the third most common reason for a 483 (violation) was because of inadequate content of investigations or not completing an investigation in a timely manner. One of the most common mistakes made by the write...

Our Facility Expanding With The Market

According to recent trends in the market, the global contract pharmaceutical manufacturing industry is increasing at an average annual rate of 7.5% and is predicted to reach $79.24 billion in revenue by the year 2019. The market research firm, Vision...

Maximizing Efficiency for Our Clients

A goal of any pharmaceutical manufacturer is the pursuit of the most efficient equipment available. This equipment can increase output, reduce downtime, cut costs, and increase overall productivity while also adhering to strict cGMP requirements. The...

Why We Give

In Atlanta, Georgia, the Boys & Girls Club decided to do a Christmas experiment. 83% of the children that attend the B&G Club are low-income with some of the families not even being able to afford a Christmas tree. The children were asked what one th...

The QP in the EU

If you are a US-based company manufacturing in the US and you export your drug products in the EU, either by yourself or through a partner, you need to know EU requirements and you will face inspections based on those EU requirements.

Why It's Never Too Early to Start Considering Clinical Supplies as Part of Your Development Program

All too often the planning process for clinical supplies begins after the clinical program is set in stone and the clock is ticking. It is not uncommon to have less than 30 days from first discussions to having a requirement for supplies to be at cli...

Technical Writing in the Pharmaceutical Industry

Technical writing is not a new idea. Any type of communication written for and about industry and business with a focus on products and/or services is technical writing. Almost everyone within a company has written a form of technical document – from...

Drug Delivery Methods and Therapies for Cancer Treatment

Cancer is a widely known disease involving abnormal and uncontrolled cell proliferation resulting in solid tumor development or blood cancer conditions. Therefore, when it comes to fighting cancer, the aim is to kill the cancerous cells and/or inhibi...

PMP: Exposure to Global Project Management Methodology

At Piramal Pharma Solutions customer satisfaction is of utmost importance and we strive to meet our customers’ needs in every way we can. Our main goal is to deliver quality products within scope while still keeping budgets and timelines under contro...