Dear Partners,

Necessitated by the unprecedented situation created by Covid-19, several industry events and tradeshows across the world have been postponed or stand cancelled. While we were looking forward to meet you, we at Piramal Pharma Solutions have had to take several precautionary measures to protect both our employees and customers, worldwide.

As we move forward in these extraordinary times, we want to assure you that that we are operational by taking the right safety measures and abundant precautions to ensure that we continue to support you and your patients.

While all of us are working remotely for now, you can schedule a discussion with us and we would be glad to help ensure you meet your pharmaceutical development and supply needs and thereby, your clinical and commercial timelines.

Please feel free to reach out to us at:

Our best wishes to colleagues, friends and family.

Best Regards,
Piramal Pharma Solutions

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Synthetic Chemistry

The specialized team at Piramal Discovery Solutions (PDS) makes it one of the most reputed service providers for mg to kg scale discovery chemistry requirements and boasts of a broader experience in preparing high quality small molecule NCEs. PDS is proficient in developing methodologies, including the synthesis of single, multi-step, small arrays as well as designing of the focused libraries for use in hit-to-lead and lead optimization projects.

Access to the scientific literature (ACS amongst others) and databases such as SciFinder and Reaxys provides the team with updated details to modify and develop novel synthetic routes. The compound delivery is accompanied with characterization data including high-field NMR, and mass and purity by LC-MS/HPLC/GC. Also, the Supercritical Fluid Chromatography aids chiral separation and generates a higher throughput.

Featured Services

  • Synthesis of discrete compounds/focused series, building blocks, common intermediates
  • Scale-up of intermediates and final compounds (up to multiple 100 grams)
  • Synthesis of reference standards/impurities
  • Route finding and Route scouting activities
  • Live access to our 35000+ chemical inventory database (including 16000 unique building blocks) via a secure on the cloud software - ChemInventory allowing faster access to starting materials

Specialized Chemistry Capabilities

  • Chiral
  • Aliphatic, aromatic and heterocyclic
  • Carbohydrate
  • Peptide
  • Steroid
  • Nucleoside
  • Natural product
  • Macrolides/Macrocycles