Dear Partners,

Necessitated by the unprecedented situation created by Covid-19, several industry events and tradeshows across the world have been postponed or stand cancelled. While we were looking forward to meet you, we at Piramal Pharma Solutions have had to take several precautionary measures to protect both our employees and customers, worldwide.

As we move forward in these extraordinary times, we want to assure you that that we are operational by taking the right safety measures and abundant precautions to ensure that we continue to support you and your patients.

While all of us are working remotely for now, you can schedule a discussion with us and we would be glad to help ensure you meet your pharmaceutical development and supply needs and thereby, your clinical and commercial timelines.

Please feel free to reach out to us at:

Our best wishes to colleagues, friends and family.

Best Regards,
Piramal Pharma Solutions

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In-vitro Biology Services

Piramal’s in vitro Biology is designed to provide best in class support to our clients to enable their preclinical drug discovery, including assay development, hit identification, hit-to-lead and lead optimization, including HTS, multiplex assay development, primary/secondary functional assays, HCS, and selectivity. Our assay team can develop, and screen compounds, with miniaturization of assays achieved by using 96 and 384-well plates. Our assays are validated rigorously using tool compounds with QC established (signal: noise ratio; Z’-prime;uniformity; reproducibility).


  • In-vitro Biology offers high quality screening through-
    • Target based screening
      • Enzymes (kinases, proteases, phosphatases, dehydrogenases etc.)
      • GPCR
      • Ion Channels
      • Nuclear Receptor
      • Protein-protein interaction
    • Phenotype based screening (based on the therapeutic Indication)
  • Experienced team well versed in biochemistry, cell biology, HTS, HCS and protein engineering
  • Dedicated instrumentation to provide evaluation across multiple formats such as fluorescence (HTRF,FP FI), luminescence, alphascreen and MS
  • All of our service offerings are available under one roof, giving you a seamless experience

Some of the key instruments are listed below:

  • Liquid handling systems/Pipetting stations
    • Echo 650(Acoustic Dispensing)
    • Integra
    • Biomek i7 (Beckman Coulter) integrated with PHERAstar
    • 96-well microplate washer
  • Multimode plate readers
    • Polarstar (BMG Labtech)
    • CLARIOstar(BMG Labtech)
    • PHERAstar FSX (BMG Labtech)
    • FLIPR Penta
  • High Content Screening Instruments
    • ImageXpress Confocal Microscope (Molecular Devices)
    • Incucyte SX5
  • Multiplexing Systems
    • LSR Fortessa X20 (BD) - 18 colors
    • MESO QuickPlex SQ 120MM (MSD)
  • Bioanalytical
    • HPLCs (Agilent, Shimadzu)
    • LC-MS/MS