COVID-19

Dear Partners,

Necessitated by the unprecedented situation created by Covid-19, several industry events and tradeshows across the world have been postponed or stand cancelled. While we were looking forward to meet you, we at Piramal Pharma Solutions have had to take several precautionary measures to protect both our employees and customers, worldwide.

As we move forward in these extraordinary times, we want to assure you that that we are operational by taking the right safety measures and abundant precautions to ensure that we continue to support you and your patients.

While all of us are working remotely for now, you can schedule a discussion with us and we would be glad to help ensure you meet your pharmaceutical development and supply needs and thereby, your clinical and commercial timelines.

Please feel free to reach out to us at:
Stuart.Needleman@piramal.com

Our best wishes to colleagues, friends and family.

Best Regards,
Piramal Pharma Solutions

PiramalPharma Solutions Logo

Technology Transfer

Introduction:

In the pharmaceutical industry, “technology transfer” refers to the processes that are needed for successful progression of stages ranging from drug discovery, product development, clinical trials to full-scale commercialization or it is the transfer between development and commercialization at different sites within or outside an organization.

In pharmaceutical industry, preparation of dosage form needs scale up in/at several stages. For instance, a typical small scale laboratory development of Oral Solids involves a 0.5-2kg batch which can be scaled up to 5-10 kg and then to 20-100 kg on a pilot scale. Typically, production scale ranges from 200-1000kg. Technology transfer involves manufacturing drug product with increasing batch sizes on larger equipment or using continuous processing on pilot scale equipment.

Technology Transfer Process:

Technology-Transfer-Process

Factors Influencing Technology Transfer

Drivers for Technology Transfer –

  • Multinational pharmaceutical companies transfer technology to local manufacturers to fulfill contingency supplies.
  • To gain access to new machinery, training, know-how and business partnership.
  • Exclusive capabilities at multiple sites within an organization can be utilized.
  • To gain access to good business and manufacturing practices in the areas of product identification and formulation technology.
  • Balance cost to develop potential for competitive pricing.
  • Vertical Integration, for higher capacity utilization and lower production costs.
  • Strong economy, political stability and supportive regulatory, business & scientific environment.
  • Meeting regulatory requirements of different markets across the globe.

Barriers of Technology Transfer –

  • Lack of efficiency due to absence of automation leading to higher costs.
  • Incapability of local producers to meet International Quality Standards and gain market share.
  • Cost of prequalification at International level.
  • High labor turnover and absenteeism due to unattractive conditions of service
  • Ineffective coordination or compatibility between the sending and receiving sites or between development and manufacturing units initially.

Leveraging Piramal’s Global Network for tech transfers

Piramal utilizes its Global network to provide end to end services in Oral Solids and Sterile. Our development units are located at Ahmedabad, India and Morpeth, UK. Commercial manufacturing of Oral solids is offered through our FDA Approved sites at Morpeth and Pithampur.

Global Footprint – Tech Transfer Capabilities

Global-Footprint-–-Tech-Tra

Great!