Case Study: Lifecycle COGS reduction for a US Big Pharma

The customer had a basket of 6 on-patent products, including API and formulations, approaching expiry
The customer wanted a reduction in the COGs for these products to maintain its profitability in the late phase and off-patent stages

Developed an organizational focus on continuous improvements
- Trained all employees in Operational excellence and lean projects
- Trained key employees at Institute of Leadership management
Initiated technical process improvements, yield improvements, backward integration in API and alternative sourcing measures

Case Study: Developing and manufacturing different formulation type

Formulation of a new lozenge flavor formulation for existing nicotine smoking cessation product range
Pilot batches production for different strengths for US and Europe markets

Scale-up for initial non-GMP materials in pilot development area followed by production in GMP area for small scale, consumer taste test samples and batches for registration for stability studies and registration
Provided inputs to customer on process improvements to prevent friability / increase tablet durability
Supported clinical trials and subsequent commercial scale manufacturing through Clinical Trials supply Team and GMP manufacturing facility

Ensured alignment of all stakeholders to the expectations and needs of customer through daily meetings
Oriented internal supply chain towards customer's needs
Established collective responsibility and ownership for actions
Provided monthly monitoring of performance and transparent result sharing with the client

Consistent achievement in-stock performance above target for more than 2 years and consequently supply assurance to customer
Trusted supplier for the customer - among the top 2 suppliers for Europe